I can't get it to run on Vista either (Business mode). When I run I get a warning : "You are running Windows NT or Windows 95, the program may not run under those systems!" then on selecting create a data CD/DVD get a critical error "The drive(s) could not be initialized..." then an information "There are no compatible CDR drives reported. Some older SDR drives are not currently supported."
RMB on the desktop or start menu icon doesn't show "Run as admin" and "run as admin" is also greyed out in the advanced properties. Doing Run as admin on cdbxp.exe makes no difference to this issue.
NMSAccess service is installed, but also makes no difference (could do with a description on the service).